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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SIN3A
All Species:
15.45
Human Site:
S451
Identified Species:
30.91
UniProt:
Q96ST3
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96ST3
NP_001138829.1
1273
145175
S451
L
L
N
L
K
D
S
S
M
A
D
A
S
K
H
Chimpanzee
Pan troglodytes
XP_510682
1273
145185
S451
L
L
N
L
K
D
S
S
M
A
D
V
S
K
H
Rhesus Macaque
Macaca mulatta
XP_001103539
1273
145217
S451
L
L
N
L
K
D
S
S
M
A
D
A
S
K
H
Dog
Lupus familis
XP_535546
1240
141674
L451
A
E
A
Y
E
N
F
L
R
C
L
V
I
F
N
Cat
Felis silvestris
Mouse
Mus musculus
Q60520
1282
146164
S451
K
L
M
S
L
K
E
S
S
M
A
D
A
S
K
Rat
Rattus norvegicus
NP_001102231
1129
127784
K391
N
S
S
V
L
L
S
K
T
T
A
E
K
V
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512119
1268
144524
Q444
K
L
L
G
L
K
D
Q
S
L
A
E
A
S
K
Chicken
Gallus gallus
XP_413695
1272
145279
Q449
K
L
L
G
L
K
D
Q
S
L
A
E
A
S
K
Frog
Xenopus laevis
NP_001081937
1275
145070
Q452
K
I
L
I
P
K
D
Q
S
L
A
D
A
N
K
Zebra Danio
Brachydanio rerio
NP_001091650
1276
145765
S454
L
M
N
I
K
D
S
S
G
A
E
A
G
K
H
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188916
1290
146297
E479
T
K
D
I
S
L
D
E
A
G
K
H
G
S
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P22579
1536
174821
T555
S
P
P
T
N
G
S
T
V
H
E
A
Y
Q
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
99.8
96.4
N.A.
97.4
86.8
N.A.
90.8
91.1
82.3
78
N.A.
N.A.
N.A.
N.A.
53
Protein Similarity:
100
99.9
99.8
96.9
N.A.
98.4
87.7
N.A.
94.9
94.9
89.5
86.9
N.A.
N.A.
N.A.
N.A.
67.5
P-Site Identity:
100
93.3
100
0
N.A.
13.3
6.6
N.A.
6.6
6.6
0
66.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
93.3
100
20
N.A.
20
20
N.A.
13.3
13.3
20
86.6
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
27.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
44.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
0
0
0
0
9
34
42
34
34
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% C
% Asp:
0
0
9
0
0
34
34
0
0
0
25
17
0
0
17
% D
% Glu:
0
9
0
0
9
0
9
9
0
0
17
25
0
0
0
% E
% Phe:
0
0
0
0
0
0
9
0
0
0
0
0
0
9
0
% F
% Gly:
0
0
0
17
0
9
0
0
9
9
0
0
17
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
34
% H
% Ile:
0
9
0
25
0
0
0
0
0
0
0
0
9
0
0
% I
% Lys:
34
9
0
0
34
34
0
9
0
0
9
0
9
34
34
% K
% Leu:
34
50
25
25
34
17
0
9
0
25
9
0
0
0
9
% L
% Met:
0
9
9
0
0
0
0
0
25
9
0
0
0
0
0
% M
% Asn:
9
0
34
0
9
9
0
0
0
0
0
0
0
9
9
% N
% Pro:
0
9
9
0
9
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
25
0
0
0
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
9
9
9
9
9
0
50
42
34
0
0
0
25
34
0
% S
% Thr:
9
0
0
9
0
0
0
9
9
9
0
0
0
0
0
% T
% Val:
0
0
0
9
0
0
0
0
9
0
0
17
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _